collagenase

collagenase
Proteolytic enzyme capable of breaking native collagen. Once the initial cleavage is made, less specific proteases will complete the degradation. Collagenases from mammalian cells are metallo-enzymes and are collagen-type specific. May be released in latent (proenzyme) form into tissues and require activation by other proteases before they will degrade fibrillar matrix. Bacterial collagenases are used in tissue disruption for cell harvesting.

Dictionary of molecular biology. 2004.

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  • Collagenase — Collagénase Les collagénases sont des enzymes capables de rompre les liaisons peptidiques du collagène. Elles facilitent la destruction des structures extracellulaires lors de la pathogenèse bactérienne. Ce sont des exotoxines. La production de… …   Wikipédia en Français

  • collagenase — collagenase. См. коллагеназа. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Collagenase — matrix metallopeptidase 1 (interstitial collagenase) Identifiers Symbol MMP1 Entrez 4312 HUGO …   Wikipedia

  • Collagenase clostridium histolyticum — Clinical data Pregnancy cat. B(US) Legal status ℞ Prescription only Routes Intralesional injection …   Wikipedia

  • collagenase A, collagenase I — SYN: Clostridium histolyticum collagenase …   Medical dictionary

  • collagenase — noun Date: 1926 any of a group of proteolytic enzymes that decompose collagen and gelatin …   New Collegiate Dictionary

  • Collagénase — Les collagénases sont des enzymes capables de rompre les liaisons peptidiques du collagène. Elles facilitent la destruction des structures extracellulaires lors de la pathogenèse bactérienne. Ce sont des exotoxines. La production de collagénases… …   Wikipédia en Français

  • collagenase — n. [Gr. kolla, glue; genos, to produce; asis, denoting enzymes] A proteolytic digestive enzyme …   Dictionary of invertebrate zoology

  • collagenase — col·lag·e·nase (kə lăjʹə nās , nāz , kŏlʹə jə ) n. Any of various enzymes that catalyze the hydrolysis of collagen and gelatin. * * * …   Universalium

  • collagenase — noun An enzyme that breaks the peptide bonds in collagen …   Wiktionary

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